Uracil Derivatives and Related Compounds. V. Alkyluracil Derivatives.
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چکیده
منابع مشابه
Nucleic Acid Related Compounds. 107. Efficient Nitration of Uracil Base and Nucleoside Derivatives(1).
The 5′-phosphate ester of 5-nitro-2′-deoxyuridine (7c) is a potent mechanism-based inhibitor of thymidylate synthase.2 Compound 7c3 and 1-(â-D-arabinofuranosyl)5-nitrouracil4 have antiviral activity, and certain O-nitro esters of pyrimidine5 and purine6 nucleosides also have biological activity. The 5′-O-nitro esters of pyrimidine nucleosides function as good substrates for 5′-modification via ...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1958
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.6.490